The Silk Road, as the most famous trade route in the ancient world, has always attracted considerable attention from researchers. Economics and commerce are the main subjects of most research on the Silk Road. However, along this long route, not only were goods and wealth exchanged, but culture, language, and even religion among different peoples also interacted and influenced each other. In the third volume of A History of Zoroastrianism, Mary Boyce and Franz Grenet refer to the myth of Zoroaster among the priests of the Temple of Atargatis at Mabug. According to this legend, Zoroaster, with the help of a Thracian magician named Orpheus, succeeds in repelling an evil and annoying spirit that lives in the forests around Mabug. While Boyce and Grenet trace the origins of this legend to the period of Achaemenid rule in Syria, the most important document in this regard is The Apology of Pseudo-Meliton from the sixth or seventh century AD; that is, almost a thousand years after the fall of the Achaemenids. In addition, another source that can be considered the influence of Zoroastrian beliefs in Mabug is De Dea Syria by Lucian of Samosata, which was written in the second century AD, almost five hundred years after the fall of the Achaemenids. This time gap seriously challenges Boyce and Grenet’s view. On the other hand, considering that the Silk Road flourished and passed through Mabug at the time when both sources were composed, and also due to the proximity of this city to the Iranian border, the present study shows that the origin of this legend should be traced via the Silk Road.